Thermo Fisher Scientific PTPN13 Polyclonal Antibody
PTPN13 단백질에 특이적인 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, IHC, ICC, IP 등 다양한 응용에 사용 가능. Human 시료에 반응하며, whole serum 형태로 제공. 연구용 전용 제품으로 안정적인 신호 검출에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:1,000–1:5,000 | - |
| Immunohistochemistry (Frozen) (IHC-F) | 1:10–1:500 | - |
| Immunocytochemistry (ICC/IF) | 1:500–1:3,000 | - |
| Immunoprecipitation (IP) | 1:50–1:200 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to amino acids 1279–1883 of human FAP-1 protein (GenBank no. NP_542414.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2718760 |
Target Information
The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family, which regulates various cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This large intracellular PTP contains a catalytic domain at its C-terminus, five PDZ domains, and a FERM domain that binds to plasma membrane and cytoskeletal elements.
It interacts with and dephosphorylates Fas receptor and IκBα, suggesting a role in Fas-mediated apoptosis. Additionally, it interacts with GTPase-activating proteins, indicating a regulatory function in Rho signaling pathways.
Four alternatively spliced transcript variants encoding distinct proteins have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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