Thermo Fisher Scientific Phospho-PKC zeta (Thr560) Recombinant Rabbit Monoclonal Antibody (SN0753)

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:5,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50–1:200

Product Specifications

Product Specific Information

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.

Advantages:

• Excellent specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to large rabbit immune repertoire

Target Information

The PKC family of serine/threonine kinases, including PRKCZ (PKC zeta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC isoforms have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action, response to extracellular signals, and substrate specificity.

PKC zeta plays a key regulatory role in various cellular functions including:

• Cell growth and differentiation
• Gene expression
• Hormone secretion
• Membrane function

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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