Thermo Fisher Scientific Phospho-PKC zeta (Thr560) Recombinant Rabbit Monoclonal Antibody (SN0753)
PKC zeta 단백질의 Thr560 인산화 부위를 특이적으로 인식하는 재조합 토끼 단일클론 항체. Western blot 및 IHC(파라핀) 적용 가능. 높은 특이성과 민감도, 로트 간 일관성 및 동물유래 성분 무첨가 포뮬레이션 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SN0753 |
| Immunogen | Synthetic phospho-peptide corresponding to residues surrounding Thr560 of Human PKC zeta (aa 531–580) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809607 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages:
- Excellent specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to large rabbit immune repertoire
Target Information
The PKC family of serine/threonine kinases, including PRKCZ (PKC zeta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC isoforms have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action, response to extracellular signals, and substrate specificity.
PKC zeta plays a key regulatory role in various cellular functions including:
- Cell growth and differentiation
- Gene expression
- Hormone secretion
- Membrane function
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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