Thermo Fisher Scientific KV1.1 (KCNA1) Recombinant Rabbit Monoclonal Antibody (SN66-06)
Thermo Fisher의 KV1.1 (KCNA1) 재조합 토끼 단클론 항체로, Western blot과 IHC에 적합. 높은 특이성과 민감도를 제공하며, 로트 간 일관성이 우수. 인간, 마우스, 랫트 반응성. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:5,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SN66-06 |
| Immunogen | Synthetic peptide within Human KCNA1 aa 491–440 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809599 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
This gene encodes a voltage-gated delayed potassium channel related to the Drosophila Shaker channel. The protein has six transmembrane segments, with the S5–S6 loop forming the pore and selectivity filter.
The functional channel is a homotetramer.
- N-terminus: interacts with beta subunits affecting inactivation and expression levels
- C-terminus: complexes with PDZ domain proteins for channel targeting
Mutations in this gene are associated with myokymia and periodic ataxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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