Thermo Fisher Scientific CHOP Polyclonal Antibody
CHOP 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 인간 및 마우스 반응성. 고순도(>95%) 항원 친화 크로마토그래피 정제. 액상 형태, 1 mg/mL 농도, 장기 보관 시 -20°C 권장.
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Thermo Fisher Scientific CHOP Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids at the N-terminus of Human CHOP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803066 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
GADD153 (also known as CHOP) is a small nuclear protein that dimerizes with transcription factors C/EBP alpha and beta. The resulting complex inhibits normal C/EBP binding and function, while acquiring binding activity to non-classical, stress-related targets. Under normal conditions, CHOP expression is undetectable but becomes highly upregulated under cellular or ER stress such as tunicamycin treatment, nutrient starvation, or reducing agents affecting calcium flux across the ER membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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