Thermo Fisher Scientific MMP10 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MMP10, validated for IHC and ICC/IF applications. High purity (>95%) and antigen affinity purified. Supplied in PBS with glycerol and sodium azide, ideal for research use in tissue remodeling studies.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
- Immunocytochemistry (ICC/IF): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 351–400 of Human MMP-10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803072 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
MMP10 belongs to the matrix metalloproteinase family and is generally secreted in its pro form, which is further modified by extracellular proteinases. As a metalloproteinase, MMP10 requires zinc and calcium as cofactors for activity. It is involved in activation of pro-collagenase, catabolism of collagen, degradation of fibronectin, and tissue remodeling. In humans, the gene MMP10 is located on chromosome 11.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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