Thermo Fisher Scientific FBXL4 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested dilution: 0.2–1 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
VLETYHPGAV IRILACSANP YSPNPPAEVR WEILWSERPT KVNASQARQF

• For short-term use: store at 2–8°C up to 1 week
• For long-term storage: store at -20°C in small aliquots to prevent freeze-thaw cycles

Predicted homology:
Cow: 93% • Dog: 93% • Horse: 93% • Human: 100% • Mouse: 100% • Pig: 93% • Rabbit: 93% • Rat: 100%

Target Information

This gene encodes a member of the F-box protein family, characterized by an approximately 40 amino acid F-box motif.
F-box proteins form one of the four subunits of the ubiquitin protein ligase complex SCFs (SKP1–cullin–F-box), which function in phosphorylation-dependent ubiquitination.

F-box proteins are divided into three classes:

• Fbws: containing WD-40 domains
• Fbls: containing leucine-rich repeats
• Fbxs: containing other protein–protein interaction modules or no recognizable motifs

The protein encoded by this gene belongs to the Fbls class, containing at least nine tandem leucine-rich repeats in addition to an F-box.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.