Thermo Fisher Scientific Periostin (POSTN) Monoclonal Antibody (POSTN/3504)
인간 Periostin 단백질을 인식하는 Mouse IgG1 단일클론 항체입니다. ELISA 및 Peptide Array에 적합하며, 단백질 A/G로 정제된 액상 형태입니다. PBS 버퍼에 보관하며 4°C에서 보관, 동결 금지. 연구용으로만 사용됩니다.
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- pk
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Thermo Fisher Scientific Periostin (POSTN) Monoclonal Antibody (POSTN/3504)
Applications
- ELISA (ELISA): Assay-dependent
- Peptide Array (Array): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | POSTN/3504 |
| Immunogen | Recombinant fragment (around aa193–326) of human POSTN protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Periostin (PN), also known as osteoblast-specific factor 2 (OSF-2), is a disulfide-linked protein originally isolated as an osteoblast-specific factor. It is a secreted protein that binds heparin and functions as a ligand for α(V)β(3) and α(V)β(5) integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule, playing roles in osteoblast recruitment, spreading, and attachment.
Periostin is mainly detected in the lower gastrointestinal tract, aorta, stomach, placenta, uterus, and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression is increased by bone morphogenetic protein (BMP2) and transforming growth factor beta 1 (TGF-β1).
It contains a typical signal sequence, a cysteine-rich domain, a fourfold repeated domain homologous to insect fasciclin, and a C-terminal domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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