Thermo Fisher Scientific MCD Polyclonal Antibody
MLYCD 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 고순도의 Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MLYCD (Accession O95822), corresponding to amino acid residues L307–D357 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2853972 |
Product Specific Information
Antibody detects endogenous levels of total MLYCD.
Target Information
MCD catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide.
Malonyl-CoA is an intermediate in fatty acid biosynthesis and inhibits the transport of fatty acyl CoAs into mitochondria.
Consequently, the encoded protein acts to increase the rate of fatty acid oxidation.
It is found in mitochondria, peroxisomes, and the cytoplasm.
Mutations in this gene result in malonyl-CoA decarboxylase deficiency.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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