Thermo Fisher Scientific TBK1 Polyclonal Antibody
TBK1 단백질을 인식하는 Rabbit Polyclonal 항체로, NF-κB 및 IRF3 신호전달 연구에 적합합니다. ICC/IF에 사용 가능하며, 다양한 종에서 높은 예측 반응성을 보입니다. 액상 형태로 제공되며 4°C 단기 보관, -20°C 장기 보관이 권장됩니다.
- 카탈로그번호
- PA585253
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human NAK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.39 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792396 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Rhesus Monkey (100%), Bovine (100%).
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
TBK1 (TANK-binding kinase 1) is a serine/threonine kinase and a member of the IKK family, involved in NF-κB activation and IRF3 signaling.
It acts as a key mediator of gene expression during immune and inflammatory responses.
Phosphorylation of I-κB by the IKK complex leads to its degradation and NF-κB activation.
NAK/TBK1 activates IKKβ through direct phosphorylation and mediates IKK and NF-κB activation in response to growth factors.
It is also critical in protecting embryonic liver from apoptosis.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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