Thermo Fisher Scientific TLR9 Polyclonal Antibody
TLR9 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 Immunocytochemistry에 적합합니다. Human, Mouse, Rat에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 용액에 0.02% sodium azide를 포함하며 4°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1.0 µg/mL | View 3 publications |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Fish, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A peptide corresponding to 15 amino acids near the center of human TLR9 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152135 |
Product Specific Information
- A suggested positive control is Jurkat cell lysate.
- PA5-20203 can be used with blocking peptide PEP-0346.
Target Information
The protein encoded by this gene is a member of the Toll-like receptor family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns expressed on infectious agents and mediate cytokine production necessary for effective immunity.
This gene is preferentially expressed in immune cell–rich tissues such as spleen, lymph node, bone marrow, and peripheral blood leukocytes. Studies in mice and humans indicate that this receptor mediates cellular responses to unmethylated CpG dinucleotides in bacterial DNA to initiate an innate immune response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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