Thermo Fisher Scientific TYRO3 Recombinant Rabbit Monoclonal Antibody (14H68L29)

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

This antibody is predicted to react with Human, Monkey, Pig, Bovine, and Cat.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The specific antibody DNA sequences from immunoreactive rabbits are cloned and expressed, followed by screening to select optimal clones for production.

Advantages include:

• Enhanced specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity due to the large rabbit immune repertoire

Target Information

TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces extracellular matrix signals into the cytoplasm by binding ligands such as TULP1 or GAS6. It regulates processes including cell survival, migration, and differentiation. Ligand binding induces receptor dimerization and autophosphorylation, creating docking sites for downstream signaling molecules.

TYRO3 activation plays roles in:

• Neuronal protection from excitotoxic injury
• Platelet aggregation
• Signal transduction
• Cell adhesion and cytoskeleton reorganization

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.