Thermo Fisher Scientific TYRO3 Recombinant Rabbit Monoclonal Antibody (14H68L29)
TYRO3 단백질을 인식하는 Recombinant Rabbit Monoclonal Antibody입니다. 인간 및 설치류 시료에 반응하며, 높은 특이성과 재현성을 제공합니다. 단백질 A로 정제된 액상 형태로, 단기 4°C, 장기 -20°C 보관이 가능합니다. 연구용으로만 사용됩니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 14H68L29 |
| Immunogen | Protein corresponding to human TYRO3 (aa 790–890) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2784573 |
Product Specific Information
This antibody is predicted to react with Human, Monkey, Pig, Bovine, and Cat.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The specific antibody DNA sequences from immunoreactive rabbits are cloned and expressed, followed by screening to select optimal clones for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the large rabbit immune repertoire
Target Information
TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces extracellular matrix signals into the cytoplasm by binding ligands such as TULP1 or GAS6. It regulates processes including cell survival, migration, and differentiation. Ligand binding induces receptor dimerization and autophosphorylation, creating docking sites for downstream signaling molecules.
TYRO3 activation plays roles in:
- Neuronal protection from excitotoxic injury
- Platelet aggregation
- Signal transduction
- Cell adhesion and cytoskeleton reorganization
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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