Thermo Fisher Scientific AKT3 Recombinant Rabbit Monoclonal Antibody (10H3L10)
AKT3 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot에 적합합니다. 인간과 교차 반응하며 높은 특이성과 일관된 품질을 제공합니다. 단백질 A로 정제된 액상 형태이며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 10H3L10 |
| Immunogen | Peptides corresponding to human AKT3 (AA449–AA466, AA116–AA131) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2784572 |
Product Specific Information
This antibody is predicted to react with Monkey, Horse, Sheep, and Bovine.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, followed by screening to select optimal candidates.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
AKT3 (PKB gamma) is stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1).
It participates in various biological processes such as:
- Cell proliferation and differentiation
- Apoptosis and tumorigenesis
- Glycogen synthesis and glucose uptake
Alternatively spliced transcript variants encoding distinct isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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