Thermo Fisher Scientific Human RET, GST Tag Recombinant Protein
인간 RET 단백질을 GST 태그로 발현한 재조합 단백질로, 키나아제 활성 분석 등에 사용 가능. 곤충 세포에서 발현되며 79 kDa 크기의 액상 형태로 제공. 고순도 정제되어 있으며 -80°C에서 안정적으로 보관 가능.
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human RET, GST Tag Recombinant Protein
Applications
- Kinase Assay (KA)
Tested Dilution
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | Insect cells |
| Amino Acid Sequence | 658–1114 |
| Tag | GST-tag |
| Molecular Weight | 79 kDa |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Purified |
| Storage Buffer | 50 mM Tris-HCl (pH 7.5), 50% glycerol, 0.02% Triton X-100, 150 mM NaCl, 0.5 mM EDTA, 2 mM DTT |
| Contains | No preservative |
| Storage Conditions | -80°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
Product Specific Information
- For maximum recovery, please spin prior to use.
- Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use in original packaging until exhausted.
- For larger sizes, aliquot preparation may reduce freeze/thaw cycles; aliquots below 20 µL are not recommended.
- Never store diluted kinase.
- Properly stored at -80°C, product guaranteed for 6 months from date of purchase.
- Protein Form: Cytoplasmic
Target Information
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development and can undergo oncogenic activation via cytogenetic rearrangement. It transduces signals for cell growth and differentiation.
Mutations in the RET gene are associated with multiple endocrine neoplasia type IIA and IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been identified, with additional variants described but not biologically confirmed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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