Thermo Fisher Scientific Human RPS6KB1 (p70S6K), GST Tag Recombinant Protein

Thermo Fisher Scientific Human RPS6KB1 (p70S6K), GST Tag Recombinant Protein

Applications

• Kinase Assay (KA)

Tested Dilution: Assay-dependent
Publications: Reference available upon request

Product Specifications

Product Specific Information

• For maximum recovery, spin prior to use.
• Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use material in original packaging until exhausted.
• For larger sizes, reduce freeze/thaw cycles by preparing aliquots (do not prepare aliquots below 20 µL).
• Never store kinase diluted.
• Properly stored at -80°C, guaranteed for 6 months from date of purchase.
• Protein Form: Catalytic

Target Information

RPS6KB1 (p70S6K) is a serine/threonine kinase with two non-identical catalytic domains that phosphorylate multiple residues of the S6 ribosomal protein.
This kinase is mainly localized in the cytoplasm and plays a key role in growth factor-regulated cell proliferation, cell motility, immune response, and tissue repair pathways.
p70 S6 kinase acts downstream of phosphoinositide (PI) 3-kinase, targeting the S6 ribosomal protein to enhance protein synthesis and cell proliferation.
Amplification and overexpression of p70 S6 kinase are observed in certain breast cancer cell lines.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.