Thermo Fisher Scientific CD1a Monoclonal Antibody (6H3)
CD1a 단백질을 검출하는 Mouse IgG1 단일클론 항체로, WB, Flow Cytometry, ELISA에 적합. 인간 시료에 반응하며 비결합형 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6H3 |
| Immunogen | Purified recombinant fragment of human CD1A expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11153473 |
Product Specific Information
MA5-15828 targets CD1A in indirect ELISA, FACS, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human CD1A expressed in E. coli.
MA5-15828 detects CD1A with a predicted molecular weight of approximately 37 kDa.
Target Information
CD1a is a non-polymorphic MHC Class I-related cell surface glycoprotein expressed in association with Beta-2 microglobulin.
It is found on cortical thymocytes, Langerhans cells, dendritic cells, certain T-cell leukemias, and various other tissues.
CD1a proteins mediate the presentation of lipid and glycolipid antigens to T cells.
The human genome contains five CD1 family genes (CD1a, b, c, d, and e) clustered on chromosome 1.
CD1a localizes to the plasma membrane and recycles through vesicles of the early endocytic system.
Alternatively spliced transcript variants have been observed, though their biological validity is undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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