Thermo Fisher Scientific BMPR2 Monoclonal Antibody (3F6F8)
BMPR2 단백질을 검출하기 위한 Thermo Fisher Scientific의 단클론 항체. Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용 가능. 인간, 마우스, 비인간 영장류, 랫트 시료에 반응. Protein A 정제, 1 mg/mL 농도, PBS buffer에 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | 6 publications |
| Immunohistochemistry (IHC) | - | 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–4 µg/mL | 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:200 | - |
| Flow Cytometry (Flow) | 1:100–1:200 | - |
| ELISA | - | 1 publication |
| Immunoprecipitation (IP) | - | 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Bovine, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3F6F8 |
| Immunogen | Purified recombinant fragment of human BMPR2 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11156844 |
Product Specific Information
MA5-15827 targets BMPR2 in FACS, ICC/IF, IHC (P), and WB applications and shows reactivity with human, mouse, non-human primate, and rat samples.
Target Information
BMPR2 is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. BMP ligands are involved in endochondral bone formation and embryogenesis. Loss of BMPR2 function may contribute to primary pulmonary hypertension (PPH) and pulmonary veno-occlusive disease. BMPR2 also plays an essential role in human T-cell differentiation. BMPs signal through heteromeric complexes of type I and type II serine/threonine kinase receptors. Type II receptors bind ligands independently but require type I receptors for signaling, while type I receptors require type II receptors for ligand binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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