Thermo Fisher Scientific FOS Monoclonal Antibody (OTI2D2), TrueMAB
Human FOS 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI2D2). IHC(P) 검증 완료, 비결합형 동결건조 형태로 제공. PBS buffer(8% trehalose) 보존, -20°C 보관. 연구용으로 세포 신호전달 및 전사 조절 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:250
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D2 |
| Immunogen | Full length human recombinant protein of human FOS produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882) before use.
Target Information
FBJ murine osteosarcoma viral oncogene homolog, commonly known as Cellular proto-oncogene Fos (c-Fos), belongs to the Fos transcription factor family and is encoded by the C-FOS gene on chromosome 14.
c-Fos heterodimerizes with c-Jun to form the Activator Protein-1 (AP-1) transcription factor, which regulates transcription of genes involved in cellular signal transduction, proliferation, and differentiation.
It is phosphorylated by multiple stimuli, including growth factors and insulin, at several sites. The ERK MAPK kinase phosphorylates threonine 232, influencing nuclear localization and transcriptional activity of c-Fos.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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