Thermo Fisher Scientific Trefoil factor 2/TFF2 Monoclonal Antibody (GE16C)
인간 TFF2 단백질을 인식하는 GE16C 클론 단일클론 항체로, ELISA 등 연구용에 적합. 액상 형태로 제공되며 Protein L로 정제됨. 4°C 보관, 동결 금지. 위점막 보호 및 재생 관련 연구에 활용 가능.
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Thermo Fisher Scientific Trefoil factor 2/TFF2 Monoclonal Antibody (GE16C)
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GE16C |
| Immunogen | Synthetic peptide corresponding to a 16-amino acid C-terminal sequence of the human Trefoil factor 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein L |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Trefoil peptides are protease-resistant molecules secreted throughout the gut that play a role in mucosal healing and protection of the gastrointestinal epithelia. These peptides contain three intrachain disulfide bonds forming the trefoil motif or P-domain.
SP (spasmolytic polypeptide), also designated Trefoil factor 2 (TFF2) precursor, is a trefoil protein that functions to inhibit gastrointestinal motility and gastric acid secretion. SP may also act as a structural component of gastric mucus, stabilizing glycoproteins through carbohydrate interactions.
Downregulation of SP expression is associated with primary gastric cancer, and progressive loss of this protein may be involved in early-stage gastric carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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