Thermo Fisher Scientific Trefoil factor 2/TFF2 Monoclonal Antibody (GE16C)
인간 TFF2 단백질을 인식하는 GE16C 클론의 Mouse IgM 단일클론 항체. ELISA 등 연구용으로 사용 가능하며, Protein L 정제된 액상 형태로 제공. PBS(pH 7.4) buffer에 보존제 없이 -20°C에서 보관.
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Thermo Fisher Scientific Trefoil factor 2/TFF2 Monoclonal Antibody (GE16C)
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GE16C |
| Immunogen | Synthetic peptide corresponding to a 16-amino acid C-terminal sequence of the human Trefoil factor 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein L |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Trefoil peptides are protease-resistant molecules secreted throughout the gut that play a role in mucosal healing and protection of the gastrointestinal epithelia. These peptides contain three intrachain disulfide bonds, forming the trefoil motif or P-domain.
SP (spasmolytic polypeptide), also designated Trefoil factor 2 (TFF2) precursor, is a trefoil protein that functions to inhibit gastrointestinal motility and gastric acid secretion. SP may also act as a structural component of the gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains.
A downregulation of SP expression is associated with primary gastric cancer, and a progressive loss of this protein is likely to be involved in the early stage of the multi-step gastric carcinogenesis pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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