Thermo Fisher Scientific P2X3 Polyclonal Antibody
Rabbit polyclonal antibody against human P2X3 receptor. Validated for IHC (paraffin) at 10 µg/mL. High specificity with 100% identity in primates. Suitable for pain and sensory signaling research. For research use only.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested at 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from C-terminal cytoplasmic domain of human P2RX3 / P2X3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551422 |
Product Specific Information
- Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Monkey, Marmoset (100%)
Bat, Rabbit, Opossum (93%)
Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Horse (87%) - Antigen retrieval requires Proteinase K treatment.
Target Information
The P2X3 receptor belongs to the family of purinoceptors for ATP and functions as a ligand-gated ion channel. It may transduce ATP-evoked nociceptor activation. Mouse studies indicate its role in peripheral pain responses and urinary bladder volume reflex pathways. Selective antagonists for this receptor could have potential therapeutic applications in pain relief and urinary disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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