Thermo Fisher Scientific P2Y1 Polyclonal Antibody
Rabbit 폴리클로날 항체로 인간 및 박쥐 P2Y1 단백질을 인식. 면역조직화학(IHC)에서 2.5 µg/mL로 검증됨. 항원 친화 크로마토그래피로 정제된 액상 형태. ADP 결합에 의해 혈소판 응집 및 신경 신호 조절 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bat, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from 2nd extracellular domain of human P2RY1 / P2Y1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551426 |
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Bat (100%).
Target Information
P2Y1 is a purinergic receptor that induces platelet shape change and aggregation through ADP binding, leading to intracellular calcium mobilization via phospholipase C activation. It also mediates nitric oxide release and may modulate neuronal signal transmission. P2Y1 is expressed in various tissues, particularly in the brain. ESTs have been isolated from human embryo, lung, and placenta libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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