
Thermo Fisher Scientific Oxytocin Receptor Polyclonal Antibody
인간 Oxytocin Receptor를 인식하는 Rabbit Polyclonal 항체로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS buffer에 0.1% sodium azide가 포함되어 있습니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human Oxytocin Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551421 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Gibbon (100%)
- Monkey (94%)
Target Information
The oxytocin receptor (OXTR) belongs to the G-protein coupled receptor family. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
The receptor consists of 389 amino acids and has a molecular weight of approximately 43,000 kDa.
The oxytocin-oxytocin receptor system plays an important role as an inducer of uterine contractions during parturition and of milk ejection. Oxytocin receptors are expressed by the myoepithelial cells of the mammary gland, and in both the myometrium and endometrium of the uterus at the end of pregnancy.
Additionally, oxytocin receptors are present in the central nervous system, mediating a variety of behaviors including maternal behavior, bonding, social memory and recognition, sexual and aggressive behaviors, and stress and anxiety.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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