Thermo Fisher Scientific P2X7 Polyclonal Antibody
P2X7 폴리클로날 항체로 인간 및 비인간 영장류 시료에 반응. IHC(P) 실험에 적합하며 항원 친화 크로마토그래피로 정제됨. ATP 의존성 이온 채널 수용체 연구에 활용 가능. 장기 보관 시 -20°C에서 보관 권장.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 10–20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from internal region of human P2RX7 / P2X7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551423 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gibbon, Monkey: 100%
- Marmoset, Pig: 88%
- Mouse, Horse: 81%
Target Information
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay criteria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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