Thermo Fisher Scientific Cul3 Polyclonal Antibody
Cul3 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 Immunoprecipitation에 적합. 인간 Cullin 3의 718–768번 잔기 영역을 면역원으로 사용. 1 mg/mL 농도의 액상 형태이며 4°C에서 보관. Rat, X. laevis, X. tropicalis와 교차 반응 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 718 and 768 of human cullin 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Rat, X. laevis, and X. tropicalis
Target Information
Cullin 3 (CUL3) is a member of the human cullin gene family (CUL1, 2, 3, 4a, 4b, and 5), homologous to the S. cerevisiae cdc53 gene.
CUL1 forms a complex with human p19 skp1 and F-box protein p45 skp2, functioning as part of a ubiquitin ligase that controls proteolysis of G1 cell cycle regulatory proteins.
In contrast, CUL2 does not associate with p19 skp1 or p45 skp2 but forms a complex with the transcriptional elongation complex SIII (Elongin C, Elongin B, and VHL). The function of this association remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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