Thermo Fisher Scientific Cul3 Polyclonal Antibody
Cul3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB 및 IP 실험에 적합합니다. 사람과 생쥐에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 4°C 보관, 연구용으로만 사용됩니다.
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Thermo Fisher Scientific Cul3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 718 and 768 of human cullin 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat, X. laevis, and X. tropicalis
Target Information
Cullin 3 is a member of the human cullin gene family (CUL1, 2, 3, 4a, 4b, and 5), homologous to the S. cerevisiae cdc53 gene.
CUL1 forms a complex with human p19 skp1 and F-box protein p45 skp2. Together with cdc53 (known as CulA), these three subunits form a ubiquitin ligase that controls proteolysis of G1 cell cycle regulatory proteins.
In contrast, CUL2 does not associate with p19 skp1 and p45 skp2 but forms a complex with the transcriptional elongation complex SIII, composed of Elongin C, Elongin B, and VHL. The function of this association remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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