Thermo Fisher Scientific MEL18 Polyclonal Antibody
Thermo Fisher MEL18 Polyclonal Antibody는 인간 MEL18 단백질을 인식하는 Rabbit IgG 항체로, 면역형광(ICC/IF)에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol) 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human MEL18. Recombinant protein control fragment (Product #RP-107245) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662798 |
Product Specific Information
Immunogen sequence:
PSEGTNTSGAS ECESVSDKAP SPATLPATSS SLPSPATPSH GS
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain transcription repression of genes involved in embryogenesis, cell cycle, and tumorigenesis. This protein acts as a negative regulator of transcription and has tumor suppressor activity. Expression is detected in various tumor cells but limited in neural organs of normal tissues. Knockout studies in mice suggest this protein may negatively regulate cytokine and chemokine expression, playing an important role in lymphocyte differentiation, migration, and immune response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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