Thermo Fisher Scientific MPZL1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human MPZL1. Recombinant protein control fragment (Product #RP-107247). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MPZL1,uniProtId:O95297-1,ncbiNodeId:9606,antigenRange:195-269,antigenLength:269,antigenImageFileName:PA5-66593_MPZL1_O95297-1_Rabbit.svg,antigenImageFileNamePDP:PA5-66593_MPZL1_O95297-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2662282

Product Specific Information

Immunogen sequence: NSKRDYTGCST SESLSPVKQA PRKSPSDTEG LVKSLPSGSH QGPVIYAQLD HSGGHHSDKI NKSESVVYAD IRKN

Highest antigen sequence identity to the following orthologs - mouse 91%, rat 91%.

Target Information

Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.