Thermo Fisher Scientific NME1 Monoclonal Antibody (OTI7D6), TrueMAB

Applications and Tested Dilution

Product Specifications

Additional Formats

• Biotin (Product Code: TA700459)
• Custom conjugation available upon request

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

NME1 was identified due to its reduced mRNA transcript levels in highly metastatic cells.
Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of A (encoded by NME1) and B (encoded by NME2) isoforms.
Mutations in this gene have been found in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been identified.
Co-transcription of NME1 and the neighboring downstream gene NME2 produces naturally occurring NME1-NME2 transcripts, encoding a fusion protein sharing sequences from both genes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.