Thermo Fisher Scientific Fumarase Polyclonal Antibody, Biotin
Biotin으로 표지된 Fumarase 폴리클로날 항체로, Western blot에 적합합니다. Human 시료에 반응하며, Goat에서 생산된 IgG 타입입니다. 0.5 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-HPNDHVNKSQSSND (aa 176–189) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932930 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Target Information
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (Krebs) cycle and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic and a mitochondrial form, differing by the translation start site. The mitochondrial form undergoes removal of the N-terminal extension to produce the same mature form as in the cytoplasm. It functions as a homotetramer and is similar to thermostable class II fumarases. Mutations in this gene can cause fumarase deficiency, leading to progressive encephalopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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