
Thermo Fisher Scientific CD154 (CD40 Ligand) Polyclonal Antibody
CD154(CD40 Ligand) 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, ELISA에 사용 가능. 인간, 마우스, 랫트 반응성. 액상 형태, Affinity Chromatography로 정제. 세포막 단일 통과형 II 막단백질 검출에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 50–150 of human CD40L (NP_0000651) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.03 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805211 |
Product Specific Information
- Positive Samples: K561
- Cellular Location: Cell membrane, Single-pass type II membrane protein
- Immunogen sequence:
LDKIEDERNL HEDFVFMKTI QRCNTGERSL SLLNCEEIKS QFEGFVKDIM LNKEETKKEN SFEMQKGDQN PQIAAHVISE ASSKTTSVLQ WAEKGYYTMS N
Target Information
CD40 Ligand (CD40-L), or CD154, is a membrane glycoprotein and differentiation antigen expressed on the surface of T cells.
It stimulates B cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines.
CD40 Ligand induces cytokine production and tumoricidal activity in peripheral blood monocytes, and co-stimulates proliferation of activated T cells accompanied by production of IFN-γ, TNF-α, and IL-2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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