
Thermo Fisher Scientific Lamin B1 Polyclonal Antibody
Lamin B1 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, ELISA에 적용 가능하며, Human, Mouse, Rat 반응성. 고순도 Affinity Chromatography 정제, 액상 형태로 안정적인 연구용 시약.
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Thermo Fisher Scientific Lamin B1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 503–586 of human Lamin B1 (NP_005564.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.03 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2807652 |
Product Specific Information
- Positive Samples: Jurkat, HT-29, HeLa, U-251MG, mouse liver, mouse brain, mouse spleen, rat liver
- Immunogen Sequence:
AGVTASPPTD LIWKNQNSWG TGEDVKVILK NSQGEEVAQR STVFKTTIPE EEEEEEEAAG VVVEEELFHQ QGTPRASNRS CAIM
Target Information
Laminins are a family of extracellular matrix glycoproteins and major noncollagenous constituents of basement membranes. They are involved in cell adhesion, differentiation, migration, signaling, neurite outgrowth, and metastasis. Laminins are composed of three non-identical chains—alpha, beta, and gamma (formerly A, B1, and B2)—forming a cruciform structure.
Defects in the LMNB1 gene can cause Leukodystrophy, demyelinating, autosomal dominant, adult-onset (ADLD).
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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