Thermo Fisher Scientific LOX-1 Polyclonal Antibody
LOX-1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 ELISA에 적합. 인간 및 마우스 반응성, 고순도 Affinity Chromatography 정제. 세포막 단백질 검출에 유용하며 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:100–1:500
- Publications: View 1 publication
ELISA
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 58–273 of human OLR1 (NP_002534.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.51 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2807552 |
Product Specific Information
Immunogen sequence:
MQLSQVSDLL TQEQANLTHQ KKKLEGQISA RQQAEEASQE SENELKEMIE TLARKLNEKS KEQMELHHQN LNLQETLKRV ANCSAPCPQD WIWHGENCYL FSSGSFNWEK SQEKCLSLDA KLLKINSTAD LDFIQQAISY SSFPFWMGLS RRNPSYPWLW EDGSPLMPHL FRVRGAVSQT YPSGTCAYIQ RGAVYAENCI LAAFSICQKK ANLRAQ
Positive Samples: OVCAR3, HeLa, HepG2
Cellular Location: Cell membrane, Lipid-anchor, Membrane raft, Single-pass type II membrane protein
Target Information
LOX-1 (lectin-like oxidized LDL receptor -1) is a 40–50 kDa type II membrane glycoprotein and a class E scavenger receptor expressed by endothelial cells, macrophages, activated platelets, and smooth muscle cells.
LOX-1 binds to various ligands such as oxidized LDL (oxLDL), hypochlorite-modified HDL, aged/apoptotic cells, activated platelets, and bacteria, indicating its broad physiological roles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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