Thermo Fisher Scientific RPS19 Polyclonal Antibody
RPS19 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 ELISA에 사용 가능. Human 시료에 반응하며, Affinity Chromatography로 정제됨. PBS/glycerol buffer에 보관되며 -20°C에서 안정적. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–145 of human RPS19 (NP_0010131) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.51 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2807838 |
Product Specific Information
- Immunogen sequence:
MPGVTVKDVN QQEFVRALAA FLKKSGKLKV PEWVDTVKLA KHKELAPYDE NWFYTRAAST ARHLYLRGGA GVGSMTKIYG GRQRNGVMPS HFSRGSKSVA RRVLQALEGL KMVEKDQDGG RKLTPQGQRD LDRIAGQVAA ANKKH - Positive Samples: HL-60, PC-3, MCF7, A-549, 293T, HepG2, SW620, BxPC-3
- Cellular Location: Nucleus
Target Information
Ribosomes are organelles that catalyze protein synthesis, consisting of a small 40S subunit and a large 60S subunit. These subunits are composed of 4 RNA species and approximately 80 distinct proteins.
The RPS19 gene encodes a ribosomal protein of the 40S subunit, belonging to the S19E family. It is located in the cytoplasm. Mutations in RPS19 cause Diamond-Blackfan anemia, characterized by reduced erythroid precursors. This suggests an extra-ribosomal role in erythropoietic differentiation and proliferation. Elevated expression has been observed in some primary colon carcinomas compared to normal tissues. Multiple processed pseudogenes of RPS19 are dispersed throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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