
Thermo Fisher Scientific PIK3CG Polyclonal Antibody
Human PI3K gamma/PIK3CG 인식하는 Rabbit Polyclonal Antibody. IHC(P)에서 1:500~1:2,000 희석으로 사용 가능. 보존제가 없는 액상 형태로 제공되며, 단백질 A 및 항원 친화 크로마토그래피로 정제됨. 단기 4℃, 장기 -20℃ 보관 권장.
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the Human Pik3cg/PIK3CG |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788737 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human PI3K gamma/Pik3cg.
Target Information
PIK3CG (p110 gamma) is the sole class IB phosphatidylinositol 3-kinase family member, which along with the class IA family members, generates the important second messenger PIP2. Unlike class IA enzymes that signal downstream of receptor tyrosine kinases, PIK3CG primarily signals downstream of GPCRs. The gene product phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring and modulates extracellular signals, including those from E-cadherin-mediated cell-cell adhesion, essential for epithelial integrity. It also plays a pivotal role in regulating cytotoxicity in NK cells and is located in a commonly deleted segment of chromosome 7 associated with myeloid leukemias.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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