Thermo Fisher Scientific Human Growth Hormone Recombinant Protein

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-dependent

-

Product Specifications

Species

Human

Expression System

E. coli

Amino acid sequence

Human Growth Hormone recombinant protein contains 192 amino acids

Molecular weight

22.260 kDa

Class

Recombinant

Type

Protein

Endotoxin concentration

<0.1 ng/µg

Activity

Fully biologically active as compared to WHO reference standard at 3 U/mg.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

100 µg/mL

Purification

purified

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Product Specific Information

This is a recombinant protein suitable for use as a control in ELISA and Western blot applications.

Store lyophilized product desiccated at -20° C. Upon reconstitution, store at 4° C for 2-7 days or aliquot and store at -20° C. For long term storage add either HSA or BSA to 0.1%. Avoid repeated freeze/thaw cycles.

Reconstitute using distilled water to a concentration not less than 100 µg/mL.

Target Information

Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The GH1 gene, along with 4 additional related genes, is located at the growth hormone locus on chromosome 17. The five genes share a remarkably high degree of sequence identity. Alternative splicing results in 5 isoforms ranging from approximately 19 kDa to 24 kDa. HGH is produced by the somatotroph cells in the pituitary. It acts through binding to membrane receptors that belong to the cytokine receptor subfamily. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Mutations or deletions in the gene lead to growth hormone deficiency and short stature.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.