Thermo Fisher Scientific SEPP1 Polyclonal Antibody
인체 유래 Selenoprotein P를 인식하는 Thermo Fisher의 SEPP1 폴리클로날 항체. 면역조직화학(IHC) 검증 완료. 항원 친화 크로마토그래피로 정제된 고순도 제품. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to a region derived from internal residues of human selenoprotein P, plasma, 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636238 |
Product Specific Information
This antibody detects endogenous levels of total Selenoprotein P protein.
Target Information
A growing body of evidence relates selenium to cancer prevention, immune system function, male fertility, cardiovascular disorders, and control of aging and neurodegenerative processes.
Selenoproteins are believed to mediate most of these biomedical effects of selenium. Approximately 17 selenoproteins have been identified to date.
Although the function of many selenoproteins remains unclear, some play important roles in antioxidant mechanisms and in the regulation of signaling pathways through catalysis of thiol/disulfide exchange.
Selenoprotein M (SelM) is highly expressed in the mammalian brain and localized to perinuclear structures (Golgi/ER). The roles of SelM have not been clearly identified to date.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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