Thermo Fisher Scientific ANGPT1 Monoclonal Antibody (OTI8C5), TrueMAB
인간 ANGPT1 단백질을 인식하는 단일클론 항체로, Western blot에 적합합니다. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. 혈관 발달 및 안정성 연구에 유용하며, 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:500 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8C5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 20–320 of human ANGPT1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, an additional desalting step is recommended (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Angiopoietins are key regulators of vascular development and angiogenesis. They bind to an endothelial cell-specific tyrosine-protein kinase receptor, activating it via tyrosine phosphorylation. ANGPT1 plays a critical role in maintaining interactions between the endothelium and surrounding matrix, contributing to blood vessel maturation, stability, and early heart development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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