Thermo Fisher Scientific MSR1 Monoclonal Antibody (OTI5F9), TrueMAB
인간 MSR1 단백질(aa 197-451)에 특이적인 단일클론 항체로 Western blot에 적합. Mouse IgG1 형식이며, 비결합 상태로 제공. 1 mg/mL 농도, PBS/BSA/glycerol 완충액에 보관. -20°C에서 안정하며 반복 동결-해동은 피해야 함.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 197–451 of human MSR1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD204 gene encodes the class A macrophage scavenger receptors, which include three types (1, 2, 3) generated by alternative splicing. These macrophage-specific trimeric integral membrane glycoproteins are involved in physiological and pathological processes such as atherosclerosis, Alzheimer’s disease, and host defense.
Type 1 and 2 isoforms mediate endocytosis of modified low-density lipoproteins (LDLs). Type 3 isoform, however, does not internalize acetyl-LDL and is retained in the endoplasmic reticulum, exerting a dominant negative effect on types 1 and 2. Diseases associated with MSR1 include Barrett Esophagus and Prostate Cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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