Thermo Fisher Scientific LPA Monoclonal Antibody (4H1)
LPA 단백질을 인식하는 Mouse monoclonal antibody(클론 4H1). WB, IHC, ICC, ELISA 등 다양한 응용에 적합. Human 시료 반응성. Protein G 정제, 1 mg/mL 농도, PBS buffer 및 sodium azide 함유. 연구용 한정 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4H1 |
| Immunogen | Purified recombinant fragment of human LPA (amino acids 1823–2013) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538582 |
Product Specific Information
MA5-17111 targets LPA in indirect ELISA, ICC, IHC, IF, and WB applications and shows reactivity with human samples.
It detects LPA, which has a predicted molecular weight of approximately 501 kDa.
Target Information
The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. It constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2–43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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