Thermo Fisher Scientific Cytokeratin 17 Monoclonal Antibody (CK17)
사이토케라틴 17(CK17)을 인식하는 마우스 단클론 항체로, 인체 시료에 반응합니다. Western blot 및 파라핀 조직 IHC에 적합하며, 단백질 A로 정제된 액상 항체입니다. 세포 내 위치 확인 및 상피성 암 진단 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CK17 |
| Immunogen | A synthetic peptide corresponding to the C-terminus of cytokeratin 17 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Breast carcinoma
- Cellular location: Cytoplasm
Target Information
Cytokeratins are a subfamily of intermediate filament proteins characterized by biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately 40 kDa and 68 kDa, with isoelectric pH between 4.9 and 7.8.
Human cytokeratins are numbered 1 to 20, and their expression patterns are characteristic of epithelial type and differentiation stage.
Cytokeratin subtype expression patterns are widely used in distinguishing different epithelial malignancies. Cytokeratin antibodies assist in tumor differential diagnosis using immunohistochemistry, cytopathology, and flow cytometric assays.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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