Thermo Fisher Scientific Synaptophysin Recombinant Rabbit Monoclonal Antibody (SYP, 4503R)
Synaptophysin 단백질을 인식하는 Recombinant Rabbit Monoclonal 항체로, 인간 시료에 반응합니다. IHC(P) 검증 완료, 신경세포 및 신경내분비 종양 연구에 적합합니다. 고순도 Protein A/G 정제, 4°C 보관, 연구용 전용 제품입니다.
- 카탈로그번호
- 6855-RBM3-P0
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SYP, 4503R |
| Immunogen | Recombinant fragment (around aa 224–313) of human Synaptophysin (SYP) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Synaptophysin is a calcium-binding integral membrane glycoprotein found in presynaptic vesicles of nearly all neurons. It contains four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting a role in synaptic vesicle endocytosis. Synaptophysin is involved in regulating short- and long-term synaptic plasticity and is widely used as a marker for nerve terminals and neuroendocrine tumor differentiation. Mutations in the gene can lead to X-linked mental retardation (syndrome 96).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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