Thermo Fisher Scientific FEM1A Polyclonal Antibody
FEM1A 단백질을 인식하는 염소 유래 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 인간 단백질에 반응하며, 소와 개에서도 예측 반응합니다. 합성 펩타이드 면역원으로 제작되었으며, 항염증 신호 관련 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (GFIPEDLEAFIELH) corresponding to the C-terminus amino acids of FEM1A (aa 656–669) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10977800 |
Product Specific Information
- This antibody is predicted to react with bovine and canine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 4,000.
Target Information
FEM1A (FEM-1 homolog a), also known as EPRAP (Prostaglandin E receptor 4-associated protein), is a 669 amino acid cytoplasmic protein that belongs to the FEM-1 family.
FEM1A is present in atheromata and in macrophages derived from peripheral blood monocytes.
It may be a component of an E3 ubiquitin-protein ligase complex and functions as a substrate recognition subunit.
FEM1A is suggested to participate in anti-inflammatory signaling of macrophages via interaction with EP4.
It is down-regulated in Rhabdomyosarcoma and considered a candidate gene for polycystic ovary syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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