Thermo Fisher Scientific KLF4 Polyclonal Antibody
KLF4 단백질을 인식하는 Goat Polyclonal 항체로 Western blot에 적합. 인간에 반응하며, 소·마우스·랫과 교차 반응 예상. 액상 형태, 0.5 mg/mL 농도, -20°C 보관. 세포 분화 및 줄기세포 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (AVSDALLPSFST) corresponding to the N-terminus amino acids of KLF4 (aa 11–23) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10986894 |
Product Specific Information
- This antibody is predicted to react with bovine, mouse, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
Kruppel-like factor 4 (KLF4) protein is encoded by the KLF4 gene located on chromosome 9 in humans. Also known as gut-enriched Kruppel-like factor (GKLF) or epithelial zinc-finger protein (EZF), it belongs to a family of conserved DNA-binding zinc finger transcription factors.
KLF4 plays key roles in cellular differentiation, proliferation, and reprogramming differentiated cells into pluripotent stem cells as one of the four Yamanaka factors. It is involved in endothelial cell signaling, adipogenesis, embryogenesis, and cell cycle control.
Nuclear localization is associated with oncogenic function, while cytosolic localization is linked to tumor-suppressive effects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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