Thermo Fisher Scientific n-Myc Polyclonal Antibody
Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합한 n-Myc 폴리클로날 항체. Human, Mouse, Rat 반응성. Rabbit IgG 유래, Affinity Chromatography로 정제. PBS/glycerol buffer에 보관, -20°C에서 안정적 저장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 168–267 of human N-Myc/MYCN (NP_005369.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.22 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804154 |
Product Specific Information
- Positive Samples: SH-SY5Y, Mouse heart, Rat brain
- Cellular Location: Nucleus
- Immunogen sequence:
AGRAGAALPA ELAHPAAECV DPAVVFPFPV NKREPAPVPA APASAPAAGP AVASGAGIAA PAGAPGVAPP RPGGRQTSGG DHKALSTSGE DTLSDSDDED
Target Information
N-Myc protein is a member of the MYC family of transcription factor proteins with a basic helix-loop-helix (bHLH) domain. N-Myc is similarly regulated and functionally complementary to C-Myc in various cellular growth and differentiation processes.
The MYCN gene is a hallmark of neuroblastoma; amplification and overexpression occur in approximately 20% of neuroblastomas and are associated with advanced disease stage, rapid tumor progression, and poor prognosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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