Thermo Fisher Scientific Myeloperoxidase Recombinant Rabbit Monoclonal Antibody (PD00-20)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:5,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000

-

Immunocytochemistry (ICC/IF)

1:100

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

PD00-20

Immunogen

Synthetic peptide within Human Myeloperoxidase aa 600-700/745. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Myeloperoxidase,uniProtId:P05164-1,ncbiNodeId:9606,antigenRange:600-700,antigenLength:745,antigenImageFileName:MA5-50687_Myeloperoxidase_P05164-1_Rabbit.svg,antigenImageFileNamePDP:MA5-50687_Myeloperoxidase_P05164-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4, with 0.1% BSA, 40% glycerol

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3092896

Product Specific Information

Positive control: Human tonsil tissue, human lung tissue, human liver tissue, human spleen tissue.

Predicted band size: 84 kDa

Subcellular Location: Lysosome.

Target Information

Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer`s Disease, Familial, 1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.