Thermo Fisher Scientific Myeloperoxidase Recombinant Rabbit Monoclonal Antibody (PD00-20)
Rabbit 모노클로날 항체로 인간 Myeloperoxidase를 특이적으로 인식합니다. Western blot, IHC, ICC/IF에 적합하며 높은 민감도와 재현성을 제공합니다. Protein A로 정제된 액상 형태로, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PD00-20 |
| Immunogen | Synthetic peptide within Human Myeloperoxidase aa 600–700/745 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3092896 |
Product Specific Information
- Positive Control: Human tonsil tissue, human lung tissue, human liver tissue, human spleen tissue
- Predicted Band Size: 84 kDa
- Subcellular Location: Lysosome
Target Information
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single-chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of two light chains and two heavy chains. This enzyme generates hypohalous acids essential for the microbicidal activity of neutrophils. Diseases associated with MPO include Myeloperoxidase Deficiency and Familial Alzheimer’s Disease type 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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