Thermo Fisher Scientific RelB Polyclonal Antibody
RelB 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ELISA에 사용 가능하며 Human, Mouse, Rat에 반응. 고순도 Affinity Chromatography 정제, 안정적 PBS/glycerol buffer 보존.
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 296–436 of human RELB (NP_0065002) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.68 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804155 |
Product Specific Information
- Positive Samples: Jurkat, HeLa, DU145
- Cellular Location: Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center
Immunogen sequence:
KSTNTSELRI CRINKESGPC TGGEELYLLC DKVQKEDISV VFSRASWEGR ADFSQADVHR QIAIVFKTPP YEDLEIVEPV TVNVFLQRLT DGVCSEPLPF TYLPRDHDSY GVDKKRKRGM PDVLGELNSS DPHGIESKRR K
Target Information
The NFkB transcription factor was originally identified as a protein complex consisting of a DNA-binding subunit and an associated protein. The DNA-binding subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a unique protein derived from the amino-terminus of a precursor designated p105. A second protein, p52 (previously referred to as p49), can act as an alternative NFkB subunit. Rel B does not bind with high affinity to NFkB sites, but heterodimers between Rel B and p50 bind with an affinity comparable to p50 NFkB homodimers. Rel B/p50 heterodimers, unlike NFkB heterodimers, transactivate transcription of promoters containing kB binding sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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