Thermo Fisher Scientific PRMT1 Polyclonal Antibody
PRMT1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, ICC/IF, IP 등 다양한 응용에 적합. 인간, 마우스, 랫트 등 다양한 종에 반응하며 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:200 |
| Immunoprecipitation (IP) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminus of human PRMT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10975894 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with other PRMT proteins.
Target Information
PRMT1 is a member of the protein arginine N-methyltransferase (PRMT) family. Arginine methylation is an irreversible post-translational modification implicated in RNA processing and trafficking, receptor-mediated signaling, and transcription.
At least three types of PRMT enzymes have been identified in mammalian cells, playing essential regulatory roles through methylation of key proteins such as nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins.
The mammalian PRMT family consists of seven members sharing two large domains of homology. Increased expression of PRMT1 may play a role in various types of cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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