Thermo Fisher Scientific beta 2-Adrenergic Receptor (extracellular) Polyclonal Antibody
Beta 2-Adrenergic Receptor (extracellular) 폴리클로날 항체로 Western blot, IHC, Flow cytometry에 적합. Human, Mouse, Rat 반응성. Rabbit IgG, 항원 친화 크로마토그래피로 정제. Lyophilized 형태로 -20°C 보관.
- 카탈로그번호
- AAR-016-xxxxx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific beta 2-Adrenergic Receptor (extracellular) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Flow Cytometry (Flow) | 2.5 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)NGSRAPDHDVTQERDE, corresponding to amino acid residues 15–30 of mouse ADRB2, Extracellular, N-terminus |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.7 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: Add 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on sample size.
The antibody ships lyophilized at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C for up to 1 week. For long-term storage, aliquot and store at -20°C.
Avoid multiple freeze/thaw cycles. Centrifuge antibody preparations before use (10,000 × g, 5 min).
Target Information
Adrenergic receptors (ARs) belong to the 7-transmembrane domain G-protein-coupled receptor (GPCR) superfamily, binding endogenous catecholamines epinephrine and norepinephrine.
They exhibit significant heterogeneity, with nine known subtypes:
- Alpha-1 ARs: 1A/D, 1B, 1C
- Alpha-2 ARs: 2A, 2B, 2C
- Beta ARs: 1, 2, 3
ARs are implicated in various disease states including hypertension, cardiac dysfunction (e.g., heart failure, ischemia, arrhythmias), diabetes, glaucoma, depression, and impotence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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