Thermo Fisher Scientific alpha 1B-Adrenergic Receptor (extracellular) Polyclonal Antibody, Atto 488

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: Assay-dependent

Flow Cytometry (Flow)

• Tested Dilution: 10 µg/5x10^5 cells

Product Specifications

Product Specific Information

• Reconstitution: 50 µL double distilled water (DDW), depending on sample size
• Ships lyophilized at room temperature
• Upon arrival, store at -20°C
• Reconstituted solution: store at 4°C for up to 1 week
• For long-term storage, aliquot and store at -20°C
• Avoid multiple freeze/thaw cycles
• Centrifuge all antibody preparations before use (10,000 × g, 5 min)

Target Information

The alpha-1b adrenoceptor is an adrenergic receptor that mediates smooth muscle contraction, regulating vascular tone and blood pressure, and contributes to atherosclerosis development. Reduced expression is linked to benign prostatic hyperplasia (BPH). It can act as a proto-oncogene when constitutively activated in transfected cells. Expression is documented in adrenal gland, aorta, brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen. ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.