Thermo Fisher Scientific Phospho-STAT5 beta (Tyr694) Monoclonal Antibody (ST5P-4A9)
STAT5 beta 인산화형(Tyr694)을 특이적으로 인식하는 마우스 단일클론 항체. Western blot 및 ELISA에 적합하며, 다양한 종(인간, 마우스, 소, 양, 랫드)에 반응. 액상 형태로 제공되며 -20°C 보관.
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Thermo Fisher Scientific Phospho-STAT5 beta (Tyr694) Monoclonal Antibody (ST5P-4A9)
Applications
- Western Blot (WB): Assay-dependent
- ELISA: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Sheep, Rat |
| Published Species | Human, Mouse, Tag |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ST5P-4A9 |
| Immunogen | A synthetic tyrosine phosphorylated peptide encompassing the conserved C-terminal tyrosine phosphorylation site (Y694) of murine STAT5. This peptide is conserved in human, bovine, sheep, and rat STAT5 proteins. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533130 |
Target Information
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by receptor-associated kinases and form homo- or heterodimers that translocate to the nucleus to act as transcription activators. STAT5 beta mediates signal transduction triggered by ligands such as IL2, IL4, CSF1, and various growth hormones. It participates in TCR signaling, apoptosis, mammary gland development, and liver gene expression dimorphism. Abnormal signaling involving this protein may contribute to acute promyelocytic leukemia (APLL).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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